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| Registros recuperados: 11 | |
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| França,RF; Vieira,RP; Ferrari,EF; Souza,RA; Osorio,RAL; Prianti-Jr,ACG; Hyslop,S; Zamuner,SR; Cogo,JC; Ribeiro,W. |
| Venom of the South American rattlesnake, Crotalus durissus terrificus (Cdt), presents myotoxic and neurotoxic outcomes, but reports on its effects on the liver are scarce. This study examined the hepatotoxicity resulting from Cdt venom administration (100, 200 and 300 µg/kg) in male Wistar rats. Animals were studies at 3, 6, 9 and 12 hours after venom injection. The hepatotoxicity was assessed through serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (AP), gamma glutamyl transferase (GGT), bilirrubin and also by histopathological evaluation. All the different concentrations of Cdt venom resulted in increased levels of hepatic enzymes, when compared with the control group, except for the 100 µg/kg dose,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Crotalus durissus terrificus; Hepatotoxicity; Histology; AST; ALT; Rattlesnake; Liver enzymes; Venom. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000100007 |
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| Céspedes,N; Castro,F; Jiménez,E; Montealegre,L; Castellanos,A; Cañas,CA; Arévalo-Herrera,M; Herrera,S. |
| Crotalus durissus cumanensis, a rattlesnake endemic to Colombia and Venezuela, is considered one of the most lethal snake species in Latin America. The aim of the present study was to compare the protein content and biological activity of the venom obtained from eight specimens of C. durissus cumanensis, namely two adults from different localities of Colombia and six offspring born in captivity. Protein profiles of crude venoms were analyzed by SDS-PAGE and RP-HPLC, and biological activities were evaluated for lethality, edema, defibrination, hemolytic and coagulant activities to assess individual venoms of adults and a pool of young snake venoms. Transient edema appeared rapidly after venom inoculation, whereas hemorrhagic effect was not observed.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Snakes; Crotalus durissus cumanensis; Rattlesnake; Venom. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200009 |
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| Bordon,Karla C. F.; Wiezel,Gisele A.; Cabral,Hamilton; Arantes,Eliane C.. |
| BackgroundCrotalus durissus terrificus venom (CdtV) is one of the most studied snake venoms in Brazil. Despite presenting several well known proteins, its L-amino acid oxidase (LAAO) has not been studied previously. This study aimed to isolate, characterize and evaluate the enzyme stability of bordonein-L, an LAAO from CdtV.Methods The enzyme was isolated through cation exchange, gel filtration and affinity chromatography, followed by a reversed-phase fast protein liquid chromatography to confirm its purity. Subsequently, its N-terminal amino acid sequence was determined by Edman degradation. The enzyme activity and stability were evaluated by a microplate colorimetric assay and the molecular mass was estimated by SDS-PAGE using periodic acid-Schiff... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Crotalus durissus terrificus; L-amino acid oxidase; Rattlesnake; Enzyme activity; Enzyme stability; Chromatography; Snake venom; Yellow venom; Stabilization. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100335 |
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| Tasima,Lídia J.; Serino-Silva,Caroline; Hatakeyama,Daniela M.; Nishiduka,Erika S.; Tashima,Alexandre K.; Sant’Anna,Sávio S.; Grego,Kathleen F.; Morais-Zani,Karen de; Tanaka-Azevedo,Anita M.. |
| Abstract Background: Crotalus durissus is considered one of the most important species of venomous snakes in Brazil, due to the high mortality of its snakebites. The venom of Crotalus durissus contains four main toxins: crotoxin, convulxin, gyroxin and crotamine. Venoms can vary in their crotamine content, being crotamine-negative or -positive. This heterogeneity is of great importance for producing antivenom, due to their different mechanisms of action. The possibility that antivenom produced by Butantan Institute might have a different immunorecognition capacity between crotamine-negative and crotamine-positive C. durissus venoms instigated us to investigate the differences between these two venom groups. Methods: The presence of crotamine was analyzed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rattlesnake; Snake venom; Toxins; Venom variation; Antivenom. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100307 |
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| Panizzutti,Marcia Helena Martins; Santos,Leonilda Correia dos; Vicente,Joaquim Júlio; Muniz-Pereira,Luís Cláudio; Pinto,Roberto Magalhães. |
| The species Ophidascaris durissus sp. nov. is proposed with basis on specimens recovered from the rattlesnake Crotalus durissus L., 1758 (type host) captured in Foz do Iguaçu, Brazil (type locality). By the lack of interlabia, the new species can be compared only to O. natricis Yamaguti, 1935 from Japan and O. freitasi Hoa & Lien, 1970, from Vietnam. However, O. durissus sp. nov. differs from O. natricis mainly by the absence of internal lip papillae, location of the vulvar aperture and length of the spicules; from O. freitasi mostly by the greater number of pre-cloacal and distribution of post-cloacal papillae. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brazil; Crotalus durissus; Nematoda; Ophidascars durissus sp. nov.; Ophidia; Rattlesnake. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-81752003000100003 |
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| Bastos,Eduardo G. de M.; Araújo,Alexandre F. B. de; Silva,Hélio R. da. |
| This paper documents the presence of rattlesnakes, as an invasive species, in several municipalities of the State of Rio de Janeiro. As previous registers indicate, these snakes probably invaded at least the municipality of Valença carried by floodwaters between the decades of 1950 and 1960. In the new environment, along the margins of the Rio Preto, these snakes were able to establish new populations in deforested areas turned into cattle grazing. The presence of rattlesnake in the municipality of Barra do Piraí, a municipality that has no border with Rio Preto, however, indicates that these snakes dispersal into new areas may be facilitated by open areas, represented by pastures, created after deforestations. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Atlantic Forest; Habitat disturbance; Range expansion; Rattlesnake; Snake. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-81752005000300047 |
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| Quan,Dan; Zurcher,Kenneth. |
| Abstract Background Cardiotoxicity is a documented complication of Crotalinae envenomation. Reported cardiac complications following snake envenomation have included acute myocardial infarction, electrocardiogram abnormalities and arrhythmias. Few reports exist describing arrhythmia induced by viper envenomation and to our knowledge none describe arrhythmia induced by Crotalinae envenomation. This report concerns the first known case of atrial fibrillation precipitated by rattlesnake bite. Case presentation A 73-year-old Caucasian man with a past medical history of hypertension, hyperlipidemia, type 1 diabetes mellitus, and a baseline first-degree atrioventricular block presented to the emergency department following a rattlesnake bite to his left lower... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Crotalidae; Rattlesnake; Bite; Envenomation; Snakebite; Atrial fibrillation. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100503 |
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| Registros recuperados: 11 | |
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